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Genome Sequencing Center Opens in Santa Fe

Wed, Nov 07, 2007

The National Center for Genome Resources (NCGR) today announced the official opening of The New Mexico Genome Sequencing Center, a-state-of-the-art center featuring two Illumina Genome Analyzer Systems. The Center is capable of sequencing about 400 million bases a day which corresponds to determining the code of life of 30 infectious disease agents a week or the entire human genome in two months. The opening of this center places New Mexico at the forefront in the nation in genome research.

"Genome sequencing promises to transform medicine. With these systems, researchers around the State can now able to undertake pioneering studies of the molecular causes of diseases, which aids in understanding, prevention, diagnosis and personalized treatment. We also are sequencing a variety of crops, which will allow us to develop new uses for those crops and breed improved crops that can withstand severe weather or disease," explained Dr. Stephen F. Kingsmore, President of NCGR.

The New Mexico Genome Sequencing Center is a partnership between NCGR and the New Mexico Institute of Mining and Technology (New Mexico Tech). It was made possible through the concerted efforts of New Mexico Governor Bill Richardson, Senators Pete Domenici and Jeff Bingaman and the New Mexico Legislature, specifically Senator Carlos Cisneros and Representative Nick Salazar.

A genome is an organism's complete set of instructions for all the activities of every cell, tissue and organ. The genome is made up of deoxyribonucleic acid (DNA), a chemical that has two strands, each made up of four chemical units, called nucleotide bases. The human genome contains approximately 3 billion of these bases. Infectious disease genomes are much smaller ranging in size from thousands to several hundred million bases.

Genome sequencing determines the exact order of the bases. The genome is broken into small DNA fragments and loaded into a sequencing machine. After determining the exact order of the bases in the fragments, a computer assembles them into continuous stretches: the genome sequence.

Some of the genome sequencing projects NCGR is currently engaged in include studying the fruit rot, leaf spot or green wilt of chili peppers, that will help farmers control infestation; discovering the genetic basis of schizophrenia and infectious disease outcomes; studies to understand food allergy; as well as new alternative raw biomaterials for the energy industry.

NCGR's mission is improving health, nutrition and the environment by genome sequencing and analysis.

Source: NCGR

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